Dr. Christina Ferousi

Postdoctoral Researcher


Contact Information

phone:+30 210 7723158

email: cferousi@chemeng.ntua.gr

Research Interests

My main research focus is the identification and characterization of prokaryotic and eukaryotic enzymes that can be implemented into not only the targeted hydrolysis of lignocellulosic biomass, but also the enzymatic degradation of synthetic polymers.

Education and Work Experience

Postdoctoral Research Fellow                                    2018-2020

Inorganic Electronic Structure
and Reactivity Group

Department of Chemistry and Chemical Biology

Cornell University, USA


PhD Environmental Microbiology                                      2017

Department of Microbiology

Faculty of Science

Radboud University, the Netherlands


Thesis: New insights into synthesis and function of heme c proteins of
anammox bacteria


MSc Biology; Major in Microbiology                                  2013

Radboud University, the Netherlands


BSc, Biology                                                                     2009

National & Kapodistrian University of Athens, Greece



Versantvoort W., Hienerwadel R., Ferousi C., van der Velden P.,
Berthomieu C., van Niftrik L., Baymann F. Spectroscopic insights into the
mechanism of anammox hydrazine synthase. Biochim Biophys Acta Bioenerg 2023, 1863, preprint.

Zerva, A., Pentari, C., Ferousi, C., Nikolaivits, E., Karnaouri, A., & Topakas, E., Recent advances on key enzymatic activities
for the utilization of lignocellulosic biomass. Bioresource Technol 2021, 342, 126058.

Ferousi C., Schmitz, R. A., Maalcke, W. J., Lindhoud, S., Versantvoort, W., Jetten, M. S. M., Reimann J., Kartal, B., Characterization of a nitrite-reducing octaheme hydroxylamine oxidoreductase
that lacks the tyrosine cross-link. J Biol Chem 2021, 296, 100476.

Ferousi C.; Majer, S. H.; DiMucci I. M.;
Lancaster K. M., Biological and Bioinspired Inorganic N-N Bond-Forming
Reactions. Chem Rev 2020,
120, 12, 5252–5307.

Ferousi C.; Lindhoud, S.; Baymann, F.; Hester, E. R.; Reimann, J.; Kartal, B., Discovery of a functional, contracted heme-binding
motif within a multiheme cytochrome. J Biol Chem 2019, 294, 16953-16965.

Dietl, A.; Maalcke, W. J.; Ferousi, C.; Jetten, M. S. M.; Kartal,
B.; Barends, T. R. M., A 60-heme reductase complex from an anammox bacterium shows an extended electron transfer pathway. Acta Crystallogr D 2019, 75, 333-341.

Akram, M.; Dietl, A.; Mersdorf, U.; Prinz, S.; Maalcke, W.; Keltjens, J.; Ferousi C.; De Almeida, N. M.; Reimann, J.; Kartal, B.; Jetten, M. S. M.; Parey, K.; Barends, T. R. M., A 192-heme electron transfer network in the hydrazine dehydrogenase complex. Sci Adv 2019, 5 (4), eaav4310.

Ferousi C.; Lindhoud, S.; Baymann, F.; Kartal, B.; Jetten, M. S.; Reimann, J., Iron assimilation and utilization in anaerobic ammonium oxidizing bacteria. Curr Opin Chem Biol 2017, 37, 129-136.

De Almeida, N. M.; Wessels, H. J.; De Graaf, R. M.; Ferousi, C.; Jetten, M. S. M.; Keltjens, J. T.; Kartal, B., Membrane-bound electron transport systems of an anammox bacterium: A complexome analysis. Biochim Biophys Acta Bioenerg 2016, 1857, 1694-704.

Dietl, A.; Ferousi, C.; Maalcke, W. J.; Menzel, A.; De Vries, S.; Keltjens, J. T.; Jetten, M. S.; Kartal, B.; Barends, T. R., The inner workings of the hydrazine synthase multiprotein complex. Nature
2015, 527, 394-397.

De Almeida, N. M.; Neumann, S.; Mesman, R. J.; Ferousi, C.; Keltjens, J. T.; Jetten, M. S.; Kartal, B.; Van Niftrik, L., Immunogold Localization of Key Metabolic Enzymes in the Anammoxosome and on the Tubule-Like Structures of Kuenenia stuttgartiensis. J. Bacteriol. 2015, 197, 2432-2441.

Ferousi C.; Speth, D. R.; Reimann, J.; Op den Camp, H. J.; Allen, J. W.; Keltjens, J. T.; Jetten, M. S., Identification of the type II cytochrome c maturation pathway in anammox bacteria by comparative genomics. BMC Microbiol 2013, 13, 265.